The Definitive Guide to Adaptiiv: 3D Printing Software for Patient-Specific Radiation Therapy
Introduction: The Shift to Patient-Specific RT Accessories
The integration of custom medical 3D printing into clinical workflows represents a critical evolution in radiation oncology. Historically, clinical teams relied on standard, manually fabricated wax or rubber materials that often failed to conform accurately to complex patient anatomies. This traditional manual method introduces significant air gaps, which can severely compromise the predictability, accuracy, and homogeneity of the radiation dose delivered to the skin and underlying tissue.
Adaptiiv Medical Technologies addresses these operational and clinical challenges by replacing manual fabrication with automated, software-driven solutions. The company provides a regulatory-cleared software platform engineered to convert patient DICOM data into highly accurate digital models that can be 3D printed directly at the oncology center or procured via an off-site fulfillment network.
What Does Adaptiiv Do?
To understand the clinical utility of this platform, the following data points outline its primary functions in a clinical setting:
Automates Patient-Specific RT Accessories: Generates digital STL models for uniform boluses, modulated electron boluses, and brachytherapy surface applicators tailored to precise individual patient anatomy.
Reduces Air Gaps in Radiation Therapy: By perfectly conforming to the patient’s skin (e.g., chest walls, extremities, noses), the custom 3D printed bolus mitigates dosimetric uncertainties caused by air cavities.
Improves Dose Distribution in Oncology: Facilitates exact manipulation of electron beam depth and radioactive source trajectory, ensuring the prescribed dose reaches the target clinical volume accurately while sparing healthy tissue.
Integrates with Treatment Planning Systems: Seamlessly imports CT and MRI DICOM data, allowing clinicians to export modified structures back into the TPS for dose calculation and validation before final 3D printing.
By utilizing Adaptiiv, radiation oncology departments can standardize their accessory creation process, resulting in highly improved patient reproducibility and quantifiable reductions in treatment setup time at the linear accelerator.
Adaptiiv Company Overview
Adaptiiv Medical Technologies Inc. operates as a specialized medical software and 3D printing technology provider within the radiation oncology sector. The organization focuses on replacing conventional, manually fabricated radiotherapy accessories with highly precise, software-engineered alternatives.
To provide procurement teams and healthcare administrators with a clear corporate profile, the following data table outlines the foundational entity details:
| Entity Attribute | Corporate Details |
| Full Company Name | Adaptiiv Medical Technologies Inc. |
| Founding Year | 2016 |
| Founders | Peter Hickey, Dr. James Robar, Alex Dunphy |
| Chief Executive Officer (CEO) | Peter Hickey |
| Global Headquarters | Halifax, Nova Scotia, Canada |
Adaptiiv Company History & Milestones
Since its inception, Adaptiiv has focused its operational roadmap on clearing regulatory hurdles and establishing OEM integrations that allow 3D printing to function within standard clinical environments. The timeline below highlights the critical product launches and regulatory milestones that have defined Adaptiiv’s growth from a specialized software startup to an integrated oncology infrastructure provider.
Strategic Partnerships, Acquisitions & Industry Recognition
To maintain its competitive advantage in the HealthTech market, Adaptiiv has prioritized strategic partnerships over outright acquisitions, embedding its software directly into the hardware supply chains of leading medical and technology manufacturers.
The Varian Medical Systems Partnership: A landmark integration ensuring Adaptiiv software is fully compatible with Varian’s Eclipse™ Treatment Planning System and BRAVOS™ afterloader systems, allowing seamless DICOM data transfer without disrupting existing clinical IT infrastructure.
HP Multi Jet Fusion (MJF) Collaboration: Adaptiiv formalized a partnership with HP to utilize their industrial-grade MJF 3D printing technology for the On Demand fulfillment network. This ensures high-throughput, dimensionally accurate production using validated, tissue-equivalent materials like Ultrasint® TPU01.
Industry Awards: The company’s focus on clinical precision has been recognized with various HealthTech innovation awards, specifically highlighting their role in improving postmastectomy radiation therapy (PMRT) workflows and reducing patient setup times.
Adaptiiv Financials & Key Metrics
For healthcare procurement teams and IT administrators evaluating enterprise software stability, assessing the financial health of vendor partners is a standard procedure. The company operates as a privately held entity, meaning its equity is not publicly traded. However, based on industry intelligence and investment disclosures, the following financial metrics highlight its current market standing.
Estimated Annual Revenue: Industry data platforms estimate the annual revenue for Adaptiiv to be between $2 million and $4.9 million. This figure reflects its targeted B2B software-as-a-service (SaaS) and on-demand manufacturing models within the specialized radiation oncology sector.
Total Funding Rounds: The enterprise has raised approximately $14.3 million in venture funding across 9 total rounds. Reaching its Series B funding stage in August 2025, the firm secured investments from institutional backers such as Innovacorp and HP Tech Ventures.
Employee Count: Maintaining a lean, highly specialized workforce, current estimates place the Adaptiiv employee count between 30 and 50 active professionals. These roles are primarily concentrated in software engineering, medical physics, and clinical application support.
Market Capitalization: As a privately funded HealthTech startup backed by venture capital, it does not have a public market cap. Procurement vetting should instead focus on its Series B backing and sustained capital raises as indicators of operational viability.
Industry & Market Position
Industry Classification & Market Segment
Adaptiiv operates within the highly regulated intersection of HealthTech, Medical Device Software, and 3D Printing in Radiation Oncology. Procurement and IT administrators categorize the company under the following B2B segments:
Primary Industry: Medical Device Software.
Target Market Segment: Radiation Oncology Departments, Medical Physics, and Clinical Engineering.
Core Application: Automating the design of patient-specific, 3D printed radiotherapy (RT) accessories and brachytherapy surface applicators.
Competitive Advantages
The primary competitive differentiators for Adaptiiv center on its regulatory standing, algorithmic automation, and integrated hardware ecosystem.
Regulatory Cleared Workflows: Unlike general-purpose CAD software or open-source slicers, the platform is FDA 510(k) cleared, CE Marked, and ISO 13485 certified specifically for radiation therapy applications. This immediately satisfies the strict compliance requirements of hospital IT and medical physics departments.
Algorithmic Automation: The Modulated Electron Bolus (MEB) software algorithm automatically calculates and adjusts bolus thickness to manipulate electron beam depth, achieving target dose homogeneity without the need for manual, time-consuming tuning within a Treatment Planning System.
Turnkey Fulfillment Network: The Adaptiiv On Demand service allows clinics to access highly precise, tissue-equivalent 3D-printed accessories without the capital expenditure (CapEx) or quality assurance (QA) burden of purchasing and maintaining medical-grade 3D printers in-house.
Key Competitors and Comparison
While traditional, manually fabricated wax or rubber uniform boluses remain the most common indirect competition, the company faces direct competition from specialized oncology manufacturers and broader medical 3D printing entities.
.decimal: A primary legacy competitor in the radiation oncology space, .decimal provides custom bolus fabrication and tissue compensators.
Comparison: While .decimal historically relied heavily on milling machinable wax alongside 3D printing for bolus design, Adaptiiv operates as a dedicated 3D printing software ecosystem with native Treatment Planning System (TPS) interoperability and an expansive on-demand network specifically optimized for advanced flexible materials.
Materialise: A global leader in 3D printing software, Materialise offers the Mimics medical suite which can be used to generate medical models.
Comparison: Materialise targets a broad spectrum of medical disciplines (e.g., orthopedics, surgical guides). In contrast, Adaptiiv is built exclusively for the complex dosimetric requirements and DICOM imaging workflows specific to radiation oncology.
3D Systems (VSP® Bolus): Offers an FDA-cleared solution for creating 3D printed radiotherapy accessories.
Comparison: 3D Systems is fundamentally an industrial hardware and materials manufacturer that developed an adjacent software layer. Adaptiiv focuses exclusively on the clinical software ecosystem, establishing strategic partnerships with hardware leaders like HP (utilizing Multi Jet Fusion technology) and Varian to provide a highly specialized, hardware-agnostic workflow.
Core Radiation Therapy (RT) Software Modules
The foundation of the Adaptiiv clinical ecosystem is its suite of regulatory-cleared software modules. Designed to replace legacy manual fabrication methods, the Adaptiiv platform automates the creation of patient-specific RT accessories, ensuring precise and reproducible dose delivery. By integrating custom medical 3D printing directly into the clinical workflow, oncology centers utilizing Adaptiiv can generate highly accurate 3D printed bolus and brachytherapy applicators derived directly from individual patient anatomy.
Modulated Electron Bolus (MEB) Software
The Adaptiiv Modulated Electron Bolus (MEB) Software provides an algorithmic, automated solution for Modulated Electron Radiation Therapy (MERT). This module generates patient-specific, modulated-thickness boluses, eliminating the need for time-intensive, manual tuning within a Treatment Planning System (TPS).
To capture the clinical utility for medical physics teams, the MEB software operates under the following parameters:
Manipulates Electron Beam Depth: Automatically calculates and generates variable bolus thicknesses to precisely shift the distal edge of the electron dose distribution.
Improves Dose Homogeneity: Protects underlying healthy tissue and critical structures while ensuring complete target volume coverage.
Workflow Optimization: Reduces the 3D printed bolus design time from hours of complex manual TPS manipulation to a streamlined, automated export process.
3D Brachytherapy Software & Nova Surface Applicator
For High-Dose-Rate (HDR) brachytherapy treatments, the Adaptiiv 3D Brachytherapy Software module enables the precise engineering of custom surface applicators. This module powers the design of the FDA-cleared Nova Surface Applicator, which serves as a highly customized alternative to standard, flat-surfaced Valencia applicators.
Key operational benefits of the brachytherapy module include:
Customized Trajectory Optimization: Engineers precise radioactive source tunnels tailored to the specific topography of superficial lesions.
Applicator Conformity: Conforms directly to highly irregular and uneven patient surfaces, minimizing the air gaps often associated with rigid, non-customized applicators.
Seamless Afterloader Integration: Generates patient-specific RT accessories fully compatible with industry-standard afterloader systems, ensuring highly accurate radioactive source delivery.
Uniform / Photon Bolus Software
Designed for External Beam Radiation Therapy (EBRT), the Adaptiiv Uniform / Photon Bolus Software module generates standard, fixed-thickness 3D printed boluses that conform perfectly to complex patient anatomies.
This module addresses the direct operational challenges of traditional bolus application:
Complex Anatomy Adaptation: Accurately fits highly irregular surface areas that are difficult to cover with standard materials, such as chest walls (critical for postmastectomy radiation therapy), noses, and extremities.
Air Gap Elimination: Mitigates the dosimetric uncertainties and skin sparing effects caused by air cavities typically found under rigid or poorly fitted sheet rubber and wax boluses.
Reproducible Daily Setup: Provides a rigid, custom-fit accessory that ensures exact placement by radiation therapists, standardizing the setup process for every daily treatment fraction.
Turnkey Manufacturing & Fulfillment Services
For oncology centers seeking to integrate custom medical 3D printing without the capital expenditure (CapEx) or operational burden of maintaining hardware in-house, Adaptiiv provides comprehensive turnkey manufacturing services. This model allows clinical facilities to bypass 3D printer and material validation for oncology, directly outsourcing production to ISO 13485-certified facilities.
Adaptiiv On Demand
Adaptiiv On Demand operates as a pay-as-you-go fulfillment service, specifically structured for clinics that prefer an outsourced manufacturing pipeline. Medical physicists and dosimetrists utilize the Adaptiiv software to design high-quality, patient-specific RT accessories, such as the FDA-cleared Nova Surface Applicator.
Upon design completion, the digital STL files are transmitted to the manufacturing network. The clinical and operational metrics for this service include:
Regulated Production: Adaptiiv then 3D prints the accessory at their own regulated facilities utilizing validated technologies like HP Multi Jet Fusion and tissue-equivalent materials (e.g., Ultrasint TPU01).
Direct Clinical Shipping: Finished patient-specific RT accessories are shipped directly to the clinic, eliminating in-house post-processing and quality assurance (QA) burdens for hospital clinical engineering teams.
Predictable Turnaround Times: Operations adhere to strict fulfillment schedules (typically 3-5 business days for standard fits), ensuring timely delivery for scheduled patient treatment cycles.
Zero Hardware Investment: Eliminates the need to purchase, commission, and maintain medical-grade 3D printers on-site.
3D Printed Moulds
As an alternative to direct printing with flexible SLA or FDM materials, Adaptiiv offers a specialized 3D Printed Moulds solution. This application allows users to design and 3D print rigid, patient-specific moulds that can be filled with standard, tissue-equivalent materials available within the clinic.
The primary benefits of utilizing the 3D Printed Moulds workflow include:
Alternative Fabrication: Gives clinics an alternative way to create customized boluses using existing clinical supplies.
Cost-Effective Production: Eliminates the necessity for expensive flexible filaments and specialized extrusion hardware.
Clinical Versatility: Ideal for highly specific anatomical topographies where pourable tissue-equivalent materials provide optimal conformity and density characteristics without the need for advanced in-house printing infrastructure.
Technical Ecosystem, Interoperability & Integrations
The clinical viability of any medical software relies heavily on its interoperability with existing multi-million dollar oncology infrastructures. The Adaptiiv platform is engineered to function within these established IT environments, ensuring secure data transfer and regulatory compliance without disrupting standard clinical operations.
Treatment Planning System (TPS) Integration
A critical operational requirement for medical physicists is seamless Treatment Planning System (TPS) integration. The Adaptiiv workflow is designed to ensure dosimetric accuracy through a continuous, closed-loop data cycle:
Data Ingestion: Imports patient DICOM data directly from CT or MRI scans into the interface.
Accessory Customization: Clinicians utilize the software to design the patient-specific RT accessory or 3D printed bolus based on the contoured anatomy.
TPS Verification: The modified structure is exported back into the TPS, allowing the clinical team to calculate the radiation dose and verify dosimetric agreement before manufacturing.
Final Export: Once the dose is verified, the software generates a precise STL file optimized for medical 3D printing.
How Adaptiiv Integrates with Varian Eclipse and HP Multi Jet Fusion
To minimize IT overhead and hardware bloat, Adaptiiv has established native partnerships with industry-leading Original Equipment Manufacturers (OEMs).
Varian Eclipse 3D Printing Integration: The software is officially compatible with Varian’s Eclipse Workstations. IT administrators can co-locate the Adaptiiv 3D Bolus and Brachytherapy software directly on their existing on-premise Eclipse hardware, eliminating the need for standalone, dedicated workstations.
Varian BRAVOS Compatibility: The platform verifies hardware compatibility with major afterloader systems, including native support for the Varian BRAVOS ecosystem to ensure accurate radioactive source delivery.
HP Multi Jet Fusion in Radiation Oncology: For the Adaptiiv On Demand fulfillment service, the company partners directly with HP. By utilizing industrial-grade HP Multi Jet Fusion (MJF) 3D printing technology, the fulfillment centers can produce high-fidelity, tissue-equivalent accessories at scale.
Native Integrations & API Availability
Beyond Varian, the platform maintains robust interoperability standards across the broader radiation oncology sector.
Native Integrations: The software supports seamless DICOM data transfer with all major TPS platforms utilized in modern clinics, including RayStation (RaySearch Laboratories) and Monaco (Elekta).
API Availability: Adaptiiv currently focuses on locked, regulatory-cleared workflows rather than offering an open API for custom clinical builds. This closed-system architecture is a deliberate compliance strategy designed to maintain strict adherence to FDA 510(k) and ISO 13485 standards, ensuring that all patient-specific RT accessories generated remain within strictly validated clinical parameters.
Deployment Options
IT directors evaluating the platform can select deployment architectures that align with their hospital’s specific cybersecurity and data governance protocols.
On-Premise Installation: The primary software modules can be installed directly on local clinical workstations or internal hospital servers. This deployment ensures that all protected health information (PHI) and DICOM data remains entirely behind the healthcare facility’s internal firewall.
Adaptiiv On Demand (Cloud/SaaS Fulfillment): Hospitals utilizing the turnkey manufacturing service transmit secure, anonymized STL files to the centralized production network. This operates as a secure service model, maintaining strict HIPAA compliance and data integrity during the external file transfer process.
Hardware Validation & Quality Assurance
In clinical oncology, the transition from software design to physical manufacturing requires stringent regulatory oversight. To support institutions printing in-house, Adaptiiv provides an extensive operational framework designed to ensure that all generated patient-specific RT accessories meet exacting dosimetric standards.
3D Printer and Material Validation Services
For hospital IT and medical physics departments, managing the quality assurance (QA) of new hardware is a significant barrier to entry. Adaptiiv has systematically mitigated this operational bottleneck by performing rigorous, proprietary hardware testing.
To ensure compliance and clinical safety, the Adaptiiv 3D printer and material validation for oncology encompasses the following protocols:
Extensive Testing Investment: The company has invested thousands of hours validating specific commercial 3D printers and biocompatible filaments to guarantee consistent dimensional accuracy and spatial resolution.
Supported Print Technologies: The validation framework covers both Fused Deposition Modeling (FDM) and Stereolithography (SLA) printing technologies.
Regulatory Compliance: By utilizing strictly validated hardware and material combinations, clinical engineering teams ensure that the in-house manufacturing process adheres to the stringent quality requirements associated with FDA-cleared workflows.
Material Science: Validating TPU01 and Flexible Resins for Clinical Use
Medical physicists require printing materials with highly specific densities and predictable dosimetric profiles. Adaptiiv addresses this technical necessity through advanced material science validation.
When commissioning 3D printed flexible bolus materials, the platform specifically validates industrial-grade polymers tailored for radiation therapy:
Validated Elastomers: The ecosystem supports advanced materials like Forward AM’s Ultrasint® TPU01 (utilized heavily in HP Multi Jet Fusion printers for the Adaptiiv On Demand service) and flexible SLA resins, such as Liqcreate Premium Flex.
Dosimetric Agreement: During the clinical commissioning process, these tissue-equivalent 3D printing materials achieve excellent dosimetric agreement with the established Treatment Planning System (TPS).
Hounsfield Unit Overrides: To accurately calculate radiation dose, physicists must apply a precise Hounsfield Unit override for 3D printed bolus structures. For example, specific flexible resins are validated to be overridden to exactly 300 HU to perfectly match their physical density in the TPS.
Depth Dose Metrics: Commissioning data confirms that the dosimetric depths of R90, R80, and R50 for these validated materials consistently agree within 1 mm of standard water phantom baseline measurements.
Navigating Regulatory and Compliance Standards
For hospital risk management teams, clinical engineering departments, and procurement officers, deploying unverified clinical technology introduces severe liability. Unlike open-source slicers or general-purpose CAD programs, the Adaptiiv platform is engineered strictly for the highly regulated radiation oncology sector. By maintaining a rigorously vetted compliance profile, the company mitigates the institutional risk associated with adopting custom medical 3D printing workflows.
To satisfy enterprise procurement requirements and global healthcare regulations, Adaptiiv maintains the following core regulatory clearances:
FDA 510(k) Cleared Radiotherapy Software: The software ecosystem holds strict FDA 510(k) clearance. This validation ensures that the United States Food and Drug Administration recognizes the technology as safe and effective for generating patient-specific RT accessories, protecting hospitals from the legal liabilities of using off-label design tools.
CE Mark Radiation Software: For international clinical deployment, Adaptiiv software carries the CE Mark, certifying compliance with the stringent health, safety, and environmental protection standards mandated for medical devices within the European Economic Area (EEA).
ISO 13485 Certified Medical 3D Printing: The organization operates under a Quality Management System (QMS) that is fully ISO 13485 certified. This internationally recognized standard demonstrates that Adaptiiv maintains strict, auditable quality controls throughout the entire software design, hardware validation, and physical manufacturing lifecycle of their medical devices.
Calculating the ROI of 3D Printed Accessories
To justify the integration of new clinical technology, oncology center administrators and IT procurement teams must evaluate the quantifiable return on investment (ROI). Transitioning from the manual, labor-intensive fabrication of traditional radiotherapy accessories to the automated production of 3D-printed devices yields immediate operational, financial, and clinical dividends.
By standardizing the accessory creation process with Adaptiiv, healthcare facilities can track ROI across three critical administrative metrics:
Reducing Radiation Therapy Setup Time: Standard wax or rubber boluses often require significant daily manipulation by radiation therapists to achieve an acceptable fit on the treatment couch. Because a custom 3D printed bolus is engineered for an exact anatomical match, facilities report reducing radiation therapy setup time at the treatment unit by up to 30%. This operational efficiency directly increases the daily throughput capacity of multi-million dollar linear accelerators.
Improving Patient Reproducibility in Oncology: The rigid or precisely flexible nature of custom-fit accessories ensures exact, standardized placement for every daily treatment fraction. This significantly reduces the need for repeat patient imaging or mid-treatment setup corrections, fundamentally improving patient reproducibility in oncology workflows.
Mitigating Dosimetric Errors: The precision of 3D-printed accessories reduces maximum air gap dimensions by up to 40% compared to conventional methods. This high-fidelity conformity is especially critical for eliminating air gaps in postmastectomy radiation therapy (PMRT), where highly uneven chest wall topography frequently compromises dose homogeneity and increases the risk of underdosing the clinical target volume.
Predictable Fulfillment Supply Chain: For clinics leveraging the outsourced manufacturing model, supply chain reliability is guaranteed. The Adaptiiv On Demand service provides highly predictable turnaround times, delivering standard TrueFit accessories in 3 to 5 business days and specialized TrueFlex models in 5 to 7 business days. This consistency allows administrators to schedule patient treatment cycles with absolute confidence.
Clinical Validation & Institutional Adoption
For healthcare administrators and chief medical physicists, the integration of new clinical technology requires robust real-world evidence. The efficacy of Adaptiiv is validated through extensive institutional adoption across leading global oncology centers. By analyzing specific 3D printed bolus case studies, facilities can benchmark the expected Adaptiiv clinical outcomes and operational improvements.
The following real-world evidence highlights how major institutions utilize the Adaptiiv software platform to solve complex dosimetric challenges:
Sutter Health (Sacramento, CA, USA): In their clinical evaluation, Sutter Health utilized the Adaptiiv ecosystem to address the complexities of postmastectomy radiation therapy (PMRT). The institutional feedback highlighted a significant reduction in air gaps during treatment delivery. The ability to design a non-uniform, modulated bolus allowed the clinical team to precisely shape the treatment dose, directly improving dose homogeneity across the chest wall. The customized fit also resulted in positive feedback from radiation therapists regarding the ease of daily setup.
Saint Luke’s Hospital (Dublin, Ireland): Prior to implementing the software, the clinical team at Saint Luke’s Hospital faced challenges with complex bolus applications on irregular patient anatomies. The adoption of Adaptiiv enabled the facility to confidently fabricate solutions for these difficult cases. The hospital reported immediate clinical outcomes, including notably reduced setup times on the treatment couch, enhanced reproducibility across daily fractions, and substantially improved patient comfort in radiation therapy.
By standardizing accessory fabrication through Adaptiiv, these oncology centers demonstrate that transitioning to custom 3D-printed devices directly translates to measurable improvements in both clinical precision and operational workflow.
Pricing & Plans for Adaptiiv Solutions
For B2B procurement teams evaluating medical software, the pricing and plans for Adaptiiv solutions are structured to accommodate different clinical capacities and capital expenditure (CapEx) strategies. The company utilizes a flexible procurement model, allowing oncology administrators to choose between an operational expenditure (OpEx) pay-per-print structure or a traditional annual software licensing model for in-house manufacturing.
Procurement officers should note that precise cost structures for these enterprise tiers depend on the specific modules required (e.g., Modulated Electron Bolus vs. 3D Brachytherapy), the number of clinical user seats, and the historical volume of patient-specific RT accessories generated by the facility annually.
The comparison table below outlines the detailed tier breakdown for Adaptiiv deployments, comparing the in-house software licensing structure against the turnkey fulfillment service.
| Procurement Tier | Description | Financial Structure | Best Clinical Fit |
| Adaptiiv On Demand (Pay-Per-Print) | Access to the software platform with physical manufacturing and fulfillment handled by regulated off-site facilities. | Variable Operational Expenditure (OpEx). Clinics are billed on a pay-per-device basis. | Facilities seeking to avoid hardware CapEx, 3D printer maintenance, and internal QA burdens. |
| Software Licensing (In-House) | Annual software license allowing clinical teams to design and physically manufacture accessories on their own validated 3D printers. | Fixed Annual Subscription + Hardware Capital Expenditure (CapEx) for 3D printers and materials. | High-volume centers equipped with existing clinical engineering teams and validated medical 3D printers. |
| Enterprise Network Licensing | Custom multi-site deployment of Adaptiiv software integrated directly into a broader hospital network’s IT infrastructure. | Custom Annual Licensing based on user seats, treatment volume, and multi-site TPS integrations. | Large-scale hospital networks requiring standardized, cross-departmental radiation oncology workflows. |
Frequently Asked Questions (FAQ) About Adaptiiv
To assist medical physicists, IT directors, and oncology administrators in their procurement and technical research, the following section directly answers the most critical, high-intent questions regarding the Adaptiiv platform.
What is a 3D printed Modulated Electron Bolus (MEB)?
A Modulated Electron Bolus (MEB) is a patient-specific, variable-thickness 3D-printed accessory. The Adaptiiv MEB software automates the design of this bolus to precisely manipulate the depth of an electron beam during radiation therapy. This ensures uniform dose coverage across irregular patient anatomy while protecting underlying healthy tissue.
How does Adaptiiv integrate with existing oncology systems?
Adaptiiv integrates directly into standard clinical workflows by utilizing DICOM data protocols. The software is specifically engineered for interoperability with major industry hardware and software, including native compatibility with Varian’s Eclipse Workstations and BRAVOS afterloader systems, allowing facilities to utilize their existing IT infrastructure.
How do you export and import DICOM data between Adaptiiv and a Treatment Planning System (TPS)?
Patient CT or MRI scans are imported via standard DICOM routing from the imaging system to the Adaptiiv software. Once the clinical team designs the accessory, the modified structure is exported back to the TPS (such as Varian Eclipse or RayStation) via DICOM RT Structure Sets for final dose calculation and verification.
Are 3D-printed radiotherapy accessories created with Adaptiiv FDA-cleared?
Yes, the core software platform and its specific modules, including the Nova Surface Applicator, hold FDA 510(k) clearance. Additionally, the software carries the CE Mark and is governed by an ISO 13485 certified Quality Management System, ensuring all generated accessories meet strict regulatory compliance standards.
What specifications does Adaptiiv look for when validating an FDM or SLA 3D printer?
When validating 3D printers for clinical oncology, the company tests hardware for stringent dimensional accuracy (typically yielding sub-millimeter agreement with digital models), spatial resolution, and material extrusion consistency. This ensures the printer can reliably reproduce the exact dosimetric properties required for patient treatment without mid-print failures.
What is the turnaround time for the Adaptiiv On Demand fulfillment service?
For clinics utilizing the outsourced turnkey manufacturing service, delivery is highly predictable. Adaptiiv On Demand typically fulfills standard rigid accessories (TrueFit) within 3 to 5 business days, and flexible, specialized accessories (TrueFlex) within 5 to 7 business days, allowing administrators to confidently schedule patient treatment cycles.
Can our clinical engineering team use an existing in-house 3D printer with Adaptiiv software?
Yes, facilities can utilize existing in-house printers, provided the hardware meets the necessary clinical validation standards. The software exports standard STL files that are compatible with a wide range of commercial FDM and SLA printers. However, facilities are responsible for their own internal Quality Assurance (QA) if the specific printer and material combination falls outside the officially validated Adaptiiv ecosystem.
What tissue-equivalent materials are validated for medical 3D printing in radiation therapy?
The platform validates highly specific industrial-grade polymers to ensure predictable dosimetric profiles. This includes flexible SLA resins (like Liqcreate Premium Flex) and advanced elastomer powders like Forward AM’s Ultrasint® TPU01, which is utilized heavily in HP Multi Jet Fusion printers within the On Demand network. These materials achieve excellent dosimetric agreement with water phantoms during commissioning.
How do Adaptiiv custom 3D applicators compare to standard Valencia applicators?
Standard Valencia applicators feature a rigid, flat surface, which can introduce significant air gaps when applied to uneven patient topography, such as facial lesions. Adaptiiv custom 3D brachytherapy applicators conform directly to the patient’s unique anatomy, eliminating air gaps and allowing for highly precise, customized radioactive source trajectory optimization.
How does the software handle changes in patient anatomy during a radiation treatment cycle?
If a patient experiences significant anatomical changes (such as weight loss or tumor shrinkage) mid-treatment, a new CT scan is acquired. The updated DICOM data is rapidly imported back into the Adaptiiv interface. Because the software automates the design process, a new, perfectly contoured patient-specific accessory can be generated, verified in the TPS, and 3D printed within hours to resume accurate treatment.
Leadership Teams:
Adaptiiv Profile Structure:
Name:
Adaptiiv Medical Technologies Inc.
Industry:
Medical Device Software
HealthTech
3D Printing in Radiation Oncology
Founded:
2016
Founders:
Peter Hickey
Dr. James Robar
Alex Dunphy
CEO:
Peter Hickey
Headquarters:
1559 Barrington Street, Suite 200-D, Halifax, NS, Canada B3J 1Z8
Global Footprint:
Deployed in clinical settings across 18+ countries globally
Ownership Structure:
Privately Held (Venture Capital Backed)
Total Funding & Stage:
Approximately $14.3 Million Total Funding (across 9 rounds)
Latest Round: Series B (August 2025)
Annual Revenue:
Estimated $2 million – $4.9 million
Number of Employees:
Estimated 30 – 50 active professionals
Target Audience:
Medical Physicists
Radiation Oncologists
Dosimetrists
Oncology Center Administrators and Clinical Engineering Teams
Core Product Lines:
Modulated Electron Bolus (MEB) Software
3D Brachytherapy Software
Nova Surface Applicator
Uniform / Photon Bolus Software
Adaptiiv On Demand (Turnkey Fulfillment)
3D Printed Moulds Solution
Key OEM Partnerships & Integrations:
Varian Medical Systems (Native compatibility with Eclipse™ Workstations and BRAVOS™ afterloader systems)
HP (Multi Jet Fusion industrial 3D printing technology for the On Demand network)
RaySearch Laboratories (RayStation TPS integration)
Elekta (Monaco TPS integration)
Regulatory Clearances & Certifications:
FDA 510(k) Cleared Radiotherapy Software
CE Mark (European Economic Area compliance)
TGA Approval (Australia)
ISO 13485 Certified Quality Management System (QMS)
NAICS and SIC Codes:
NAICS: 513210 (Software Publishers), 339112 (Surgical and Medical Instrument Manufacturing)
SIC: 7372 (Prepackaged Software), 3842 (Orthopedic, Prosthetic, and Surgical Appliances and Supplies)
Website:
Location:
1559 Barrington Street, Suite 200-D, Halifax, NS, Canada B3J 1Z8